MEB Science Day 2020

The Medicines Evaluation Board (MEB) would like to announce the MEB Science Day 2020. The theme of the day will be 'Replacement, reduction and refinement of animal studies'. 

Questions that will be discussed during the meeting include: What are the developments in 3R (replacement, reduction and refinement)? How can we leverage these developments in regulatory practice? What are the challenges and opportunities when it comes to animal reduction? What will the future bring?

When?

Thursday 13 February 2020 from 12.00 – 18.00

Where?

Auditorium, Jaarbeurs Utrecht

Registration

Registration is possible through this form: MEB Science Day 2020 Registration Form

Programme

Chair of the day:
dr. Marjon Pasmooij, programme manager MEB Science Program

12.00 – 13.00    
Registration and lunch

13.00 – 13.05    
Opening and welcome
drs. Hugo Hurts, executive director MEB

13.05 – 13.30    
Realising an optimal safety and efficacy assessment with a minimum of animal studies: MEB experience with 3Rs                      
dr. Peter van Meer, non-clinical assessor Pharmacology, Toxicology and Pharmacokinetics MEB

13.30 – 14.00    
Replacement of in vivo assays in Vaccines batch release testing. The VAC2VAC EU project and a Vaccines manufacturer’s perspective
dr. Jean-Francois Dierick, Expert Analytical Method Validation GSK, Co-leader of VAC2VAC WP5

14.00 – 14.20    
Potency tests in animals are not precise. The inherent variability of in vivo potency tests for vaccines
Coen Stalpers, PhD Utrecht University, quality assessor MEB

14.20 – 14.50    
Break & Poster session

14.50 – 15.20    
Applying the 3Rs in Toxicology and Regulatory Sciences
dr. Fiona Sewell, Programme Manager Toxicology and regulatory sciences, human health effects NC3R

15.20 – 15.50    
Advanced in vitro models for drug development: the complexity of simplicity
prof. Roos Masereeuw, professor of Experimental Pharmacology, Utrecht University

15.50 – 16.20    
Panel discussion
Facilitator: dr. Jan Willem van der Laan, senior assessor Pharmacology, Toxicology and Pharmacokinetics MEB

16.20 – 16.30    
Reflections on the day

16.30 – 18.00    
Drinks & networking